Sponsor Name: Unknown
Year Founded: 2012
Country: Germany
Number of teams: 18
Record-holding champions: 1. FC Saarbrücken (2), SV Waldhof Mannheim (2), Hessen Kassel (2)
Reigning champion: SC Freiburg II
Top Rated Players
Players| # | Player | Rating | |
| 1 |  | Maurice Trapp | 79 |
| 2 |  | Julian Derstroff | 78 |
| 3 |  | Daniele Gabriele | 78 |
| 4 |  | Moritz Kuhn | 78 |
| 5 |  | Jean-Yves M'Voto | 78 |
Regionalliga Südwest Clubs
| Club | Manager | Stadium | Location | |
 | 1. FSV Mainz 05 II | Unknown | Stadion am Bruchweg | Mainz |
 | FC 08 Homburg | Danny Schwarz | Waldstadion Homburg | Homburg |
 | FC Astoria Walldorf | Unknown | FC-Astoria-Stadion | Walldorf |
 | FC Giessen | Unknown | Waldstadion | Giessen |
 | FK Pirmasens | Unknown | Sportpark Husterhöhe | Pirmasens |
 | FSV Frankfurt | Unknown | Frankfurter Volksbank Stadion | Frankfurt |
 | Hessen Kassel | Unknown | Auestadion | Kassel |
 | Kickers Offenbach | Christian Neidhart | Sparda Bank Hessen Stadium | Offenbach am Main |
 | Rot-Weiß Koblenz | Unknown | Oberwerth | Koblenz |
 | SC Hessen Dreieich | Unknown | Sportpark Dreieich | Dreieich |
 | SG Sonnenhof Großaspach | Hans-Jürgen Boysen | Comtech Arena | Aspach |
 | TSG Balingen | Unknown | Au-Stadion | Balingen |
 | TSG Hoffenheim II | Unknown | Dietmar Hopp | Sinsheim |
 | TSV Eintracht Stadtallendorf | Unknown | Herrenwaldstadion | Stadtallendorf |
 | TSV Steinbach | Unknown | SIBRE-Sportpark | Steinbach |
 | VfB Stuttgart II | Marc Kienle | Waldaustadion | Stuttgart |
 | VfR Aalen | Peter Vollmann | Scholz-Stadion | Aalen |
 | Wormatia Worms | Unknown | EWR-Arena | Worms |
Regionalliga Südwest Referees
| None |
Regionalliga Südwest Club History
| Season | Club | |
| 2020/2021 |  | SC Freiburg II |
| 2019/2020 |  | 1. FC Saarbrücken |
| 2018/2019 |  | SV Waldhof Mannheim |
| 2017/2018 | | 1. FC Saarbrücken |
| 2016/2017 |  | SV Elversberg |
| 2015/2016 | | SV Waldhof Mannheim |
| 2013/2014 | | SG Sonnenhof Großaspach |
| 2012/2013 | | Hessen Kassel |
| 2011/2012 | | Hessen Kassel |